Life Sensors/UB201: UBE2D3 (UbcH5c)/UB-0201-0030
商品编号:
UB-0201-0030
品牌:
LifeSensors
市场价:
¥3300.00
美元价:
1980.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications
UBE2D3 is an E2 conjugation enzyme that is involved in the ubiquitylation of target substrates, along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5b, 88% and 89% sequence identity with UbcH5c, respectively) are the human homologues of the Sacchromyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways including the ubiquitylation of p53 and IκBα with the help of different E3 ligases (Hdm2 and SCF complexes respectively).
Info
Species | Human |
Source | E. coli |
Tag | None |
Molecular Weight | 16,687.2 Da |
Quantity | 0.8 nmol, 3.0 nmol |
Concentration | 40 µM |
Formulation | 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol |
Storage | -80°C, avoid freeze/thaw cycles |
品牌介绍
LifeSensors公司目前主要的产品有400多种,其产品主要覆盖泛素和泛素蛋白酶体通路等科学应用领域,并且产品线在不断的扩大中。公司开创了两大独家技术平台:用于细胞信号和药物发现的泛素蛋白酶体系统(UPS),以及增强目的蛋白在大肠杆菌、酵母、昆虫和哺乳动物细胞中表达与纯化的SUMO融合表达系统。 泛素蛋白酶体系统正在成为继激酶之后,药物发现的下一个机遇,必将成为未来许多新型药物的创新来源。作为泛素蛋白领域的先驱公司,药物的发现、分析化合物以及去泛素酶和泛素化酶的高通量筛选正是LifeSensors创新技术的真正亮点。此外,LifeSensors还为泛素的蛋白质组学提供众多定制技术服务,并且已经开发了各种各样的测定细胞中的生理底物或生物标志物的方法。