生命传感器/DB601-25µg Ssel/DB-0601-0025
商品编号：
DB-0601-0025
品牌：
LifeSensors
市场价：
¥5900.00
美元价：
3540.00
产品分类：
电源
公司分类：
power_pack
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specifications
The novel virulence factor, SseL was identified in Salmonella enterica serovar Typhimurium. SseL is translocated from the bacteria into the infected cell by a type III secretion system. SseL has de-ubiquitylating activity in vitro and an infection of cells with a SseL mutant leads to an accumulation of ubiquitylated proteins. This mutant strain also fails to cause macrophage cell death which has been implicated in the spread and systemic infection of Salmonella. Other serovars, including Typhi, Paratyphi A and Choleraesuis contain sequences encoding a protein nearly identical to SseL suggesting that de-ubiquitylating enzymes play an important role in the pathogenesis of other Salmonella serovars.
Info
| Amount | 25 µg |
| State | Liquid |
| MW | 37 kDa |
| Source | Salmonella Recombinant |
| Fusion Tag | His6 |
| Storage | Store at -80°C, avoiding repeated freeze-thaw cycles |
| Alternative Names | STM2287 |
| Expression Host | E. coli |
| Suggested Substrate | Ubiquitin-Rhodamine (Cat. # SI230) |
| Gene ID | sseL |
品牌介绍
LifeSensors公司目前主要的产品有400多种，其产品主要覆盖泛素和泛素蛋白酶体通路等科学应用领域，并且产品线在不断的扩大中。公司开创了两大独家技术平台：用于细胞信号和药物发现的泛素蛋白酶体系统(UPS)，以及增强目的蛋白在大肠杆菌、酵母、昆虫和哺乳动物细胞中表达与纯化的SUMO融合表达系统。 泛素蛋白酶体系统正在成为继激酶之后，药物发现的下一个机遇，必将成为未来许多新型药物的创新来源。作为泛素蛋白领域的先驱公司，药物的发现、分析化合物以及去泛素酶和泛素化酶的高通量筛选正是LifeSensors创新技术的真正亮点。此外，LifeSensors还为泛素的蛋白质组学提供众多定制技术服务，并且已经开发了各种各样的测定细胞中的生理底物或生物标志物的方法。
